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Showing posts from 2015

Cost of Sequencing Year wise

Date  Cost per Mb   Cost per Genome  Sep-01 $5,292.39 $95,263,072 Mar-02 $3,898.64 $70,175,437 Sep-02 $3,413.80 $61,448,422 Mar-03 $2,986.20 $53,751,684 Oct-03 $2,230.98 $40,157,554 Jan-04 $1,598.91 $28,780,376 Apr-04 $1,135.70 $20,442,576 Jul-04 $1,107.46 $19,934,346 Oct-04 $1,028.85 $18,519,312 Jan-05 $974.16 $17,534,970 Apr-05 $897.76 $16,159,699 Jul-05 $898.90 $16,180,224 Oct-05 $766.73 $13,801,124 Jan-06 $699.20 $12,585,659 Apr-06 $651.81 $11,732,535 Jul-06 $636.41 $11,455,315 Oct-06 $581.92 $10,474,556 Jan-07 $522.71 $9,408,739 Apr-07 $502.61 $9,047,003 Jul-07 $495.96 $8,927,342 Oct-07 $397.09 $7,147,571 Jan-08 $102.13 $3,063,820 Apr-08 $15.03 $1,352,982 Jul-08 $8.36 $752,080 Oct-08 $3.81 $342,502 Jan-09 $2.59 $232,735 Apr-09 $1.72 $154,714 Jul-09 $1.20 $108,065 Oct-09 $0.78 $70,333 Jan-10 $0.52 $46,774 Apr-10 $0.35 $31,512 Jul-10 $0.35 $31,125 Oct-10 $0.32 $29,092 Jan-11 $0.23 $20,963 Apr-11 $0.19 $16,712 Jul-11 $0.12 $10,497 Oct-11 $0.09 $

Multiple sequence alignment

Name Description Sequence Type* Alignment Type** Link Author Year License ABA A-Bruijn alignment Protein Global download B.Raphael  et al. 2004 Proprietary, without charge for educational, research and non profit. ALE manual alignment ; some software assistance Nucleotides Local download J. Blandy and K. Fogel 1994 (latest version 2007) GPL2 AMAP Sequence annealing Both Global server A. Schwartz and L. Pachter 2006 anon. fast, optimal alignment of three sequences using linear gap costs Nucleotides Global paper   software D. Powell, L. Allison and T. I. Dix 2000 BAli-Phy Tree+Multi alignment ; Probabilistic/Bayesian ; Joint Estimation Both Global WWW+download BD Redelings and MA Suchard 2005 (latest version 2015) GPL Base-By-Base Java-based multiple sequence alignment editor with integrated analysis tools Both Local or Global download R. Brodie  et al. 2004 Free, requires registration. CHAOS/DIALIGN Iterative alignment Both Local (preferred) server M. Brudno and B. Morge