About Aditya Jain

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Multiple sequence alignment

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Name Description Sequence Type* Alignment Type** Link Author Year License ABA A-Bruijn alignment Protein Global download B.Raphael  et al. 2004 Proprietary, without charge for educational, research and non profit. ALE manual alignment ; some software assistance Nucleotides Local download J. Blandy and K. Fogel 1994 (latest version 2007) GPL2 AMAP Sequence annealing Both Global server A. Schwartz and L. Pachter 2006 anon. fast, optimal alignment of three sequences using linear gap costs Nucleotides Global paper   software D. Powell, L. Allison and T. I. Dix 2000 BAli-Phy Tree+Multi alignment ; Probabilistic/Bayesian ; Joint Estimation Both Global WWW+download BD Redelings and MA Suchard 2005 (latest version 2015) GPL Base-By-Base Java-based multiple sequence alignment editor with integrated analysis tools Both Local or Global download R. Brodie  et al. 2004 Free, requires registration. CHAOS/DIALIGN Iterative alignment Both Local (preferred) server M. Brudno and B. Morge
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5 Projects completed by Aditya Jain

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1. An integrated Repository of Computational Prediction of Deleterious SNPs Involved in Pathway of Bacterial Invasion of Epithelial Cells (BIoEC) in Homo sapiens Oct 2014 – Oct 2014 Project description polyBIoECP is a directory of all the synonymous (sSNP) and non synonymous (nsSNP) polymorphisms collected using SCAN database which are associated with various genes involved in bacterial invasion of epithelial cells pathway. Â It is an effort to evaluate the phenotypic effect of all known nsSNPs of the genes involved in BIoEC pathway and to enable researchers an easy access. To further validate, this database was developed with an updated list of all validated nsSNPs from dbSNP (NCBI) and their effect on the structure and functions of the proteins along with their genomic elements such as miRNA, CNV and CpG islands. BIoECP also has a comparative analysis of native and mutant protein (using MODELLER) of the respective polymorphism validated using Ramachandran Plot. Other
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